Orbscan II anterior elevation changes following corneal collagen cross-linking treatment for keratoconus.
Identifieur interne : 003545 ( Main/Exploration ); précédent : 003544; suivant : 003546Orbscan II anterior elevation changes following corneal collagen cross-linking treatment for keratoconus.
Auteurs : Kyaw Lin Tu [Royaume-Uni] ; Ioannis M. AslanidesSource :
- Journal of refractive surgery (Thorofare, N.J. : 1995) [ 1081-597X ] ; 2009.
Descripteurs français
- KwdFr :
- Acuité visuelle (MeSH), Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Collagène (métabolisme), Cornée (anatomopathologie), Femelle (MeSH), Flavine mononucléotide (usage thérapeutique), Humains (MeSH), Jeune adulte (MeSH), Kératocône (diagnostic), Kératocône (métabolisme), Kératocône (traitement médicamenteux), Mâle (MeSH), Photosensibilisants (usage thérapeutique), Photothérapie dynamique (MeSH), Rayons ultraviolets (MeSH), Réfraction oculaire (physiologie), Stroma de la cornée (métabolisme), Topographie cornéenne (MeSH), Études rétrospectives (MeSH).
- MESH :
- anatomopathologie : Cornée.
- diagnostic : Kératocône.
- métabolisme : Collagène, Kératocône, Stroma de la cornée.
- physiologie : Réfraction oculaire.
- traitement médicamenteux : Kératocône.
- usage thérapeutique : Flavine mononucléotide, Photosensibilisants.
- Acuité visuelle, Adolescent, Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Mâle, Photothérapie dynamique, Rayons ultraviolets, Topographie cornéenne, Études rétrospectives.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Collagen (metabolism), Cornea (pathology), Corneal Stroma (metabolism), Corneal Topography (MeSH), Female (MeSH), Flavin Mononucleotide (therapeutic use), Humans (MeSH), Keratoconus (diagnosis), Keratoconus (drug therapy), Keratoconus (metabolism), Male (MeSH), Middle Aged (MeSH), Photochemotherapy (MeSH), Photosensitizing Agents (therapeutic use), Refraction, Ocular (physiology), Retrospective Studies (MeSH), Ultraviolet Rays (MeSH), Visual Acuity (MeSH), Young Adult (MeSH).
- MESH :
- chemical , metabolism : Collagen.
- diagnosis : Keratoconus.
- drug therapy : Keratoconus.
- metabolism : Corneal Stroma, Keratoconus.
- pathology : Cornea.
- physiology : Refraction, Ocular.
- chemical , therapeutic use : Flavin Mononucleotide, Photosensitizing Agents.
- Adolescent, Adult, Corneal Topography, Female, Humans, Male, Middle Aged, Photochemotherapy, Retrospective Studies, Ultraviolet Rays, Visual Acuity, Young Adult.
Abstract
PURPOSE
To analyze anterior corneal elevation changes on Orbscan II following corneal collagen cross-linking (CXL) with riboflavin.
METHODS
This retrospective study included 8 patients (14 eyes) with keratoconus who underwent CXL, with a mean follow-up of 7 months (range: 5 to 10 months). Pre- and postoperative (at last clinic attendance) anterior elevation difference maps were examined for overall patterns of change. On preoperative maps, distances from maximum anterior elevation to pupil center and to topographic geometric center were compared between the two patterns identified. Pre- and postoperative topography, best spectacle-corrected visual acuity (BSCVA), and refraction were also compared between the two patterns.
RESULTS
Two patterns of anterior elevation change were visually identified: (1) paracentral steepening, no change, or flattening centrally; and (2) central steepening. The preoperative maps of eyes that manifested pattern 1 had shorter mean distances for maximum anterior elevation to pupil center (1.70 vs. 2.27 mm) and maximum anterior elevation to geometric center (1.45 vs. 1.99 mm) than those that resulted in pattern 2. Mean maximum topographic simulated keratometry decreased (P = .004) and mean irregularity indices at 3 mm (P =.03) and 5 mm (P =.04) were reduced postoperatively in pattern 1 eyes; all increased in pattern 2 eyes. Mean BSCVA improved postoperatively for both patterns. Mean preoperative myopia decreased in pattern 1 eyes by 0.44 diopters (D), whereas it increased for pattern 2 eyes by 1.83 D.
CONCLUSIONS
Corneal shape change influenced by anisotropy of collagen distribution is a factor in the outcome of CXL treatment for keratoconus.
DOI: 10.3928/1081597X-20090707-06
PubMed: 19714796
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Orbscan II anterior elevation changes following corneal collagen cross-linking treatment for keratoconus.</title><author><name sortKey="Tu, Kyaw Lin" sort="Tu, Kyaw Lin" uniqKey="Tu K" first="Kyaw Lin" last="Tu">Kyaw Lin Tu</name><affiliation wicri:level="1"><nlm:affiliation>Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, United Kingdom. lyndon.tu@ntlworld.com</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport</wicri:regionArea><wicri:noRegion>Stockport</wicri:noRegion></affiliation></author><author><name sortKey="Aslanides, Ioannis M" sort="Aslanides, Ioannis M" uniqKey="Aslanides I" first="Ioannis M" last="Aslanides">Ioannis M. Aslanides</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19714796</idno><idno type="pmid">19714796</idno><idno type="doi">10.3928/1081597X-20090707-06</idno><idno type="wicri:Area/Main/Corpus">003469</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">003469</idno><idno type="wicri:Area/Main/Curation">003469</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">003469</idno><idno type="wicri:Area/Main/Exploration">003469</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Orbscan II anterior elevation changes following corneal collagen cross-linking treatment for keratoconus.</title><author><name sortKey="Tu, Kyaw Lin" sort="Tu, Kyaw Lin" uniqKey="Tu K" first="Kyaw Lin" last="Tu">Kyaw Lin Tu</name><affiliation wicri:level="1"><nlm:affiliation>Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, United Kingdom. lyndon.tu@ntlworld.com</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport</wicri:regionArea><wicri:noRegion>Stockport</wicri:noRegion></affiliation></author><author><name sortKey="Aslanides, Ioannis M" sort="Aslanides, Ioannis M" uniqKey="Aslanides I" first="Ioannis M" last="Aslanides">Ioannis M. Aslanides</name></author></analytic><series><title level="j">Journal of refractive surgery (Thorofare, N.J. : 1995)</title><idno type="ISSN">1081-597X</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Collagen (metabolism)</term><term>Cornea (pathology)</term><term>Corneal Stroma (metabolism)</term><term>Corneal Topography (MeSH)</term><term>Female (MeSH)</term><term>Flavin Mononucleotide (therapeutic use)</term><term>Humans (MeSH)</term><term>Keratoconus (diagnosis)</term><term>Keratoconus (drug therapy)</term><term>Keratoconus (metabolism)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Photochemotherapy (MeSH)</term><term>Photosensitizing Agents (therapeutic use)</term><term>Refraction, Ocular (physiology)</term><term>Retrospective Studies (MeSH)</term><term>Ultraviolet Rays (MeSH)</term><term>Visual Acuity (MeSH)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acuité visuelle (MeSH)</term><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Collagène (métabolisme)</term><term>Cornée (anatomopathologie)</term><term>Femelle (MeSH)</term><term>Flavine mononucléotide (usage thérapeutique)</term><term>Humains (MeSH)</term><term>Jeune adulte (MeSH)</term><term>Kératocône (diagnostic)</term><term>Kératocône (métabolisme)</term><term>Kératocône (traitement médicamenteux)</term><term>Mâle (MeSH)</term><term>Photosensibilisants (usage thérapeutique)</term><term>Photothérapie dynamique (MeSH)</term><term>Rayons ultraviolets (MeSH)</term><term>Réfraction oculaire (physiologie)</term><term>Stroma de la cornée (métabolisme)</term><term>Topographie cornéenne (MeSH)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Collagen</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Cornée</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Keratoconus</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Kératocône</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Keratoconus</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Corneal Stroma</term><term>Keratoconus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Collagène</term><term>Kératocône</term><term>Stroma de la cornée</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cornea</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Réfraction oculaire</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Refraction, Ocular</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Flavin Mononucleotide</term><term>Photosensitizing Agents</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Kératocône</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Flavine mononucléotide</term><term>Photosensibilisants</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Corneal Topography</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Photochemotherapy</term><term>Retrospective Studies</term><term>Ultraviolet Rays</term><term>Visual Acuity</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Acuité visuelle</term><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Photothérapie dynamique</term><term>Rayons ultraviolets</term><term>Topographie cornéenne</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>PURPOSE</b></p><p>To analyze anterior corneal elevation changes on Orbscan II following corneal collagen cross-linking (CXL) with riboflavin.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>This retrospective study included 8 patients (14 eyes) with keratoconus who underwent CXL, with a mean follow-up of 7 months (range: 5 to 10 months). Pre- and postoperative (at last clinic attendance) anterior elevation difference maps were examined for overall patterns of change. On preoperative maps, distances from maximum anterior elevation to pupil center and to topographic geometric center were compared between the two patterns identified. Pre- and postoperative topography, best spectacle-corrected visual acuity (BSCVA), and refraction were also compared between the two patterns.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Two patterns of anterior elevation change were visually identified: (1) paracentral steepening, no change, or flattening centrally; and (2) central steepening. The preoperative maps of eyes that manifested pattern 1 had shorter mean distances for maximum anterior elevation to pupil center (1.70 vs. 2.27 mm) and maximum anterior elevation to geometric center (1.45 vs. 1.99 mm) than those that resulted in pattern 2. Mean maximum topographic simulated keratometry decreased (P = .004) and mean irregularity indices at 3 mm (P =.03) and 5 mm (P =.04) were reduced postoperatively in pattern 1 eyes; all increased in pattern 2 eyes. Mean BSCVA improved postoperatively for both patterns. Mean preoperative myopia decreased in pattern 1 eyes by 0.44 diopters (D), whereas it increased for pattern 2 eyes by 1.83 D.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Corneal shape change influenced by anisotropy of collagen distribution is a factor in the outcome of CXL treatment for keratoconus.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19714796</PMID><DateCompleted><Year>2009</Year><Month>11</Month><Day>12</Day></DateCompleted><DateRevised><Year>2019</Year><Month>09</Month><Day>30</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1081-597X</ISSN><JournalIssue CitedMedium="Print"><Volume>25</Volume><Issue>8</Issue><PubDate><Year>2009</Year><Month>08</Month></PubDate></JournalIssue><Title>Journal of refractive surgery (Thorofare, N.J. : 1995)</Title><ISOAbbreviation>J Refract Surg</ISOAbbreviation></Journal><ArticleTitle>Orbscan II anterior elevation changes following corneal collagen cross-linking treatment for keratoconus.</ArticleTitle><Pagination><MedlinePgn>715-22</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3928/1081597X-20090707-06</ELocationID><Abstract><AbstractText Label="PURPOSE">To analyze anterior corneal elevation changes on Orbscan II following corneal collagen cross-linking (CXL) with riboflavin.</AbstractText><AbstractText Label="METHODS">This retrospective study included 8 patients (14 eyes) with keratoconus who underwent CXL, with a mean follow-up of 7 months (range: 5 to 10 months). Pre- and postoperative (at last clinic attendance) anterior elevation difference maps were examined for overall patterns of change. On preoperative maps, distances from maximum anterior elevation to pupil center and to topographic geometric center were compared between the two patterns identified. Pre- and postoperative topography, best spectacle-corrected visual acuity (BSCVA), and refraction were also compared between the two patterns.</AbstractText><AbstractText Label="RESULTS">Two patterns of anterior elevation change were visually identified: (1) paracentral steepening, no change, or flattening centrally; and (2) central steepening. The preoperative maps of eyes that manifested pattern 1 had shorter mean distances for maximum anterior elevation to pupil center (1.70 vs. 2.27 mm) and maximum anterior elevation to geometric center (1.45 vs. 1.99 mm) than those that resulted in pattern 2. Mean maximum topographic simulated keratometry decreased (P = .004) and mean irregularity indices at 3 mm (P =.03) and 5 mm (P =.04) were reduced postoperatively in pattern 1 eyes; all increased in pattern 2 eyes. Mean BSCVA improved postoperatively for both patterns. Mean preoperative myopia decreased in pattern 1 eyes by 0.44 diopters (D), whereas it increased for pattern 2 eyes by 1.83 D.</AbstractText><AbstractText Label="CONCLUSIONS">Corneal shape change influenced by anisotropy of collagen distribution is a factor in the outcome of CXL treatment for keratoconus.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tu</LastName><ForeName>Kyaw Lin</ForeName><Initials>KL</Initials><AffiliationInfo><Affiliation>Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, United Kingdom. lyndon.tu@ntlworld.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aslanides</LastName><ForeName>Ioannis M</ForeName><Initials>IM</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Refract Surg</MedlineTA><NlmUniqueID>9505927</NlmUniqueID><ISSNLinking>1081-597X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017319">Photosensitizing Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>7N464URE7E</RegistryNumber><NameOfSubstance UI="D005486">Flavin Mononucleotide</NameOfSubstance></Chemical><Chemical><RegistryNumber>9007-34-5</RegistryNumber><NameOfSubstance UI="D003094">Collagen</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Refract Surg. 2009 Dec;25(12):1051; author reply 1051-2</RefSource><PMID Version="1">20000284</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003094" MajorTopicYN="N">Collagen</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003315" MajorTopicYN="N">Cornea</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003319" MajorTopicYN="N">Corneal Stroma</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019781" MajorTopicYN="Y">Corneal Topography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005486" MajorTopicYN="N">Flavin Mononucleotide</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007640" MajorTopicYN="N">Keratoconus</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010778" MajorTopicYN="Y">Photochemotherapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017319" MajorTopicYN="N">Photosensitizing Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012029" MajorTopicYN="N">Refraction, Ocular</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014466" MajorTopicYN="N">Ultraviolet Rays</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014792" MajorTopicYN="N">Visual Acuity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>8</Month><Day>29</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>8</Month><Day>29</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2009</Year><Month>11</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19714796</ArticleId><ArticleId IdType="doi">10.3928/1081597X-20090707-06</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Aslanides, Ioannis M" sort="Aslanides, Ioannis M" uniqKey="Aslanides I" first="Ioannis M" last="Aslanides">Ioannis M. Aslanides</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Tu, Kyaw Lin" sort="Tu, Kyaw Lin" uniqKey="Tu K" first="Kyaw Lin" last="Tu">Kyaw Lin Tu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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